foxo4-dri senolytic peptide human trial 2024 The disordered p53 transactivation domain is the target of FOXO4 and the compound Molecular modelling of the FOXO4-TP53
Molecular modelling of the FOXO4 TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells eBioMedicine FOXO4 DRI improves spermatogenesis in aged mice through reducing senescence associated secretory phenotype secretion from Leydig cells ScienceDirect FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway PMC Senolytics: from pharmacological inhibitors to immunotherapies, a promising future for patients' treatment npj Aging Heterogeneity of Cellular Senescence, Senotyping, and Targeting by Senolytics and Senomorphics in Lung Diseases[v1] FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology
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